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Biologia Hematologia. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher.
This book and the individual contributions contained in it are protected under copyright by the Publisher other than as may be noted herein. Notices Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary.
Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility.
With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided i on procedures featured or ii by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications.
It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions.
Previous editions copyrighted , , This atlas is designed for a diverse audience that includes clinical laboratory science students, med- ical students, residents, and practitioners. It is also a valuable resource for clinical laboratory practitio- ners who are being retrained or cross-trained in hematology. It is not intended to be a detailed comprehensive manual for diagnosis. Chapter 1 reviews smear preparation, staining, and the appropriate area in which to evaluate cell distribution and morphology.
A table that summarizes the mor- phology of leukocytes found in a normal differ- ential, along with multiple examples of each cell type, facilitates early instruction in blood smear review. Chapter 2 schematically presents hematopoietic features of cell maturation. General cell maturation, along with an electron micrograph with labeled organelles, will help readers correlate the substruc- tures with the appearance of cells under light mi- croscopy.
Visualizing normal cellular maturation is essential to the understanding of disease processes. This correlation of schematic, electron micrograph, and Wright-stained morphology is carried through- out the maturation chapters. Figure has been reformatted to reflect recent hematopoietic theory. In addition, the chart aids readers in recognizing the anatomical sites at which each stage of maturation normally occurs. Chapters 3 to 9 present the maturation of each cell line individually, repeating the respective seg- ment of the overall hematopoietic scheme from Chapter 2, to assist the student in seeing the rela- tionship of each cell line to the whole.
In these chapters, each maturation stage is presented as a color print, a schematic, and an electron micro- graph. A description of each cell, including overall size, nuclear-to-cytoplasmic ratio, morphologic features, and reference ranges in peripheral blood and bone marrow, serves as a convenient summary.
The final figure in each of these chapters summa- rizes lineage maturation by repeating the hemato- poietic segment with the corresponding photomi- crographs. Multiple nomenclatures for erythrocyte maturation are used to accommodate use in mul- tiple settings and demographic groups. Chapters 10 to 12 present discrete cellular ab- normalities of erythrocytes, that is, variations in size, color, shape, and distribution, as well as inclu- sions found in erythrocytes.
Each variation is presented along with a description of the abnor- mality, or composition of the inclusion, and asso- ciated disorders. Because diseases are often combinations of the cellular alterations, Chapter 13 integrates morpho- logic findings into the diagnostic features of disor- ders primarily affecting erythrocytes.
In Chapter 14, nuclear and cytoplasmic changes.
Atlas de hematología clínica / Atlas of Clinical Hematology
Hematopoiesis 3. Erythrocyte Maturation 4. Megakaryocyte Maturation 5. Neutrophil Maturation 6. Monocyte Maturation 7. Eosinophil Maturation 8. Basophil Maturation 9.
CLINICAL HEMATOLOGY ATLAS, 5TH EDITION.
Biologia Hematologia. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. This book and the individual contributions contained in it are protected under copyright by the Publisher other than as may be noted herein. Notices Knowledge and best practice in this field are constantly changing.