Herniated nucleus pulposus is prolapse of an intervertebral disk through a tear in the surrounding annulus fibrosus. The tear causes pain because of the nerves in the disk, and when the disk impinges on an adjacent nerve root, a segmental radiculopathy with paresthesias and weakness in the distribution of the affected root results. Treatment of mild cases is with analgesics, activity modification, and physical therapy. Bed rest is rarely indicated. Patients with progressive or severe neurologic deficits, intractable pain, conservative treatment failure, or cauda equina syndrome with associated sphincter dysfunction may require immediate or later elective surgery eg, diskectomy, laminectomy.
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It is located within the annulus fibrosus and between the vertebral body endplates. It is composed of a thin lattice of collagen fibers type II which traverse though hydrophilic glycosaminoglycans GAGs - chondroitin sulfate, dermatan sulfate and keratan sulfate.
The glycosaminoglycans chains are covalently attached to a core-protein to form a polypeptide: proteoglycan. With aging and degeneration the glycosaminoglycans are replaced with fibrocartilage and the collagen type II replaced with type I same as the annulus fibrosus. Disc desiccation is not responsible for disc height loss, as the nucleus pulposus volume remains the same with aging, but rather due to annular bulging and end plate bowing. Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys.
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Once your system installs this update, you will not be able to upload new images. Please use another browser until we can get it fixed. On this page:. Nomenclature and standard reporting terminology of intervertebral disk herniation. Standring S editor. Gray's Anatomy 39th edition. Churchill Livingstone. Read it at Google Books - Find it at Amazon 3.
Proteoglycans of the human intervertebral disc. Electrophoretic heterogeneity of the aggregating proteoglycans of the nucleus pulposus. Edit article Share article View revision history Report problem with Article. URL of Article. Article information.
Systems: Musculoskeletal , Spine. Section: Anatomy. Support Radiopaedia and see fewer ads. Cases and figures. Case 1: intranuclear cleft - normal variant Case 1: intranuclear cleft - normal variant. Proteoglycans of intervertebral disc Proteoglycans of intervertebral disc. Loading more images Close Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Loading Stack - 0 images remaining. By System:. Patient Cases. Contact Us.
Herniated nucleus pulposus
NCBI Bookshelf. Franco L. De Cicco ; Gaston O. Camino Willhuber. Authors Franco L. De Cicco 1 ; Gaston O.
Spinal disc herniation
Spinal disc herniation is an injury to the cushioning and connective tissue between vertebrae , usually caused by excessive strain or trauma to the spine. It may result in back pain, pain or sensation in different parts of the body, and physical disability. The most conclusive diagnostic tool for disc herniation is MRI , and treatment may range from painkillers to surgery. Protection from disc herniation is best provided by core strength and an awareness of body mechanics including posture.
Herniated Nucleus Pulposus
THE DIFFFERENCES BETWEEN GENERAL BACK PAIN & HNP (HERNIA NUKLEUS PULPOSUS)